Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291874 | 0.86 | CYP2D6 (0.45) | SMN1; SMN2ALDH1A1LMNACYP2D6CYP3A4 | |
| SCHEMBL4725676 | 0.81 | HRH1 (0.35) | SMN1; SMN2TAAR1HTR2AMEN1KMT2A | |
| SCHEMBL4779771 | 0.79 | NOTUM (0.51) | SMN1; SMN2ALDH1A1ADRA1AMEN1KMT2A | |
| SCHEMBL4725344 | 0.78 | NOTUM (0.36) | SMN1; SMN2ALDH1A1LMNACYP2D6CYP2C19 | |
| SCHEMBL4777782 | 0.74 | MEN1 (0.35) | ALDH1A1LMNAMEN1KMT2AACSS2 | |
| SCHEMBL11826155 | 0.72 | RORC (0.42) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4725530 | 0.71 | CHRM3 (0.41) | SMN1; SMN2ALDH1A1LMNACYP2D6CYP3A4 | |
| Bromide SCHEMBL4727947 | 0.70 | LMNA (0.42) | SMN1; SMN2ALDH1A1LMNACYP2D6CYP3A4 | |
| SCHEMBL4725198 | 0.70 | CRHBP (0.49) | SMN1; SMN2ALDH1A1LMNACYP2D6CYP3A4 | |
| SCHEMBL8354939 | 0.69 | CYP4F2 (0.48) | ALDH1A1MEN1KMT2AACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |