Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL108667 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL10521769 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL28383261 | 0.82 | CA4 (1.00) | — | |
| Fluoride Ion SCHEMBL6175 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL4103147 | 0.82 | — | — | |
| Fluoride Ion F-18 SCHEMBL30465808 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL29197882 | 0.82 | CA4 (1.00) | — | |
| Fluoride Ion SCHEMBL3942095 | 0.82 | CA4 (1.00) | — | |
| Fluoride Ion SCHEMBL601529 | 0.82 | — | — | |
| Fluoride Ion SCHEMBL28175694 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4112038-B1 | NANO-EMULSION COMPOSITION FOR TOOTH WHITENING AND METHOD FOR PRODUCING THE SAME | AMOREPACIFIC CORP (KR) | 2025-04-16 | — | — | EP | claimed |
| EP-3962438-B1 | MAGNESIUM ION-CONTAINING MATERIALS AS WHITE PIGMENTS IN ORAL CARE COMPOSITIONS | OMYA INT AG (CH) | 2023-09-06 | — | — | EP | claimed |
| EP-3086751-B1 | STABILIZED STANNOUS COMPOSITIONS | UNIV MELBOURNE (AU) | 2023-07-12 | — | — | EP | claimed |
| US-11337902-B2 | Aqueous oral care fluoride treatment compositions, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-05-24 | — | — | US | claimed |
| EP-3892336-A1 | AQUEOUS ORAL CARE FLUORIDE TREATMENT COMPOSITIONS, AND METHODS | 3M Innovative Properties Co. (US) | 2021-10-13 | — | — | EP | claimed |
| US-12577340-B2 | Storage stable two-component dual cure dental composition | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2026-03-17 | — | — | US | disclosed |
| US-12551425-B2 | Aqueous zinc oral care compositions with fluoride | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2026-02-17 | — | — | US | disclosed |
| WO-2025235504-A1 | COMPOSITIONS AND METHODS FOR TREATING DENTAL HYPERSENSITIVITY | COLGATE-PALMOLIVE COMPANY (US) | 2025-11-13 | — | — | WO | disclosed |
| US-12465558-B2 | Curable oral care composition containing silver and fluoride | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2025-11-11 | — | — | US | disclosed |
| EP-3880156-B1 | STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2025-08-20 | — | — | EP | disclosed |
| US-20240358603-A1 | One-Part Dental Adhesive Composition for Fixing Dental Composite Materials | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-10-31 | — | — | US | disclosed |
| EP-3829527-B1 | AQUEOUS ORAL CARE THIOCYANATE-CONTAINING COMPOSITIONS, METHODS, AND KIT. | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-08-28 | — | — | EP | disclosed |
| CN-1342598-A | Process for synthesizing low-oxygen perovskite-type compound fluoride | CHANGCHUN APPLIED CHEMISTRY (CN) | 2002-04-03 | — | — | CN | disclosed |
| CN-1007768-B | MIXED LA-MG ALUMINATE AND LASER MADE FROM ALUMINATE SINGLE-CRYSTAL | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 1990-04-25 | — | — | CN | disclosed |
| EP-0297360-A1 | Dual-wavelength laser scalpel | AlliedSignal Inc. (US) | 1989-01-04 | — | — | EP | disclosed |
| US-4791927-A | Dual-wavelength laser scalpel background of the invention | ALLIED CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| CN-87108227-A | Mixed La-Mg aluminate and the laser apparatus made from this aluminate single-crystal | — | 1988-07-27 | — | — | CN | disclosed |
| US-4626558-A | Dental impression composition containing finely sized polyacrylamide | LACLEDE PROFESSIONAL PRODUCTS, INC. (US) | 1986-12-02 | — | — | US | disclosed |
| EP-0198131-A1 | Powdered alginates with polyacrylamide | LACLEDE PROFESSIONAL PRODUCTS, INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| US-4515913-A | POLYACRYLAMIDE FOR SMOOTHNESS | LACLEDE PROFESSIONAL PRODUCTS, INC. (US) | 1985-05-07 | — | — | US | disclosed |