Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 4/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 10/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729380 | 0.89 | MOGAT2 (0.49) | MOGAT2MGAT2DRD3CNR2 | |
| SCHEMBL4726300 | 0.87 | CNR2 (0.46) | MOGAT2MGAT2DRD3CNR2 | |
| SCHEMBL4729282 | 0.83 | CNR2 (0.47) | MOGAT2MGAT2DRD3CNR2KCNH2 | |
| SCHEMBL4729519 | 0.82 | DRD3 (0.44) | MOGAT2MGAT2DRD3CNR2KCNH2 | |
| SCHEMBL4726646 | 0.80 | DRD3 (0.47) | MOGAT2MGAT2DRD3CNR2 | |
| SCHEMBL4726548 | 0.77 | CRHBP (0.48) | MOGAT2DRD3DRD2KCNH2 | |
| SCHEMBL4727610 | 0.76 | UCHL1 (0.51) | MOGAT2MGAT2DRD3CNR2DRD2 | |
| SCHEMBL4730511 | 0.75 | FFAR1 (0.44) | MOGAT2MGAT2DRD3CNR2DRD2 | |
| SCHEMBL4729811 | 0.74 | ALDH1A1 (0.50) | MOGAT2MGAT2DRD3CNR2 | |
| SCHEMBL4727067 | 0.74 | TP53 (0.44) | MOGAT2MGAT2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |