Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MOGAT2 | Q3SYC2 | 3/20 | 0.43 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.43 |
| ▸ | S100A9 | P06702 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726300 | 0.90 | CNR2 (0.46) | CNR2DRD3MOGAT2MGAT2 | |
| SCHEMBL4729519 | 0.89 | DRD3 (0.44) | CNR2CCR2KCNH2DRD3MOGAT2 | |
| SCHEMBL4726646 | 0.88 | DRD3 (0.47) | CNR2DRD3MOGAT2MGAT2 | |
| SCHEMBL4726282 | 0.83 | MOGAT2 (0.44) | CNR2KCNH2DRD3MOGAT2MGAT2 | |
| SCHEMBL4729380 | 0.82 | MOGAT2 (0.49) | CNR2DRD3MOGAT2MGAT2 | |
| SCHEMBL4726498 | 0.78 | ALDH1A1 (0.44) | CCR2KCNH2DRD3 | |
| SCHEMBL4728012 | 0.77 | CES1 (0.48) | CNR2KCNH2DRD3MOGAT2MGAT2 | |
| SCHEMBL4727610 | 0.77 | UCHL1 (0.51) | CNR2KCNH2DRD3MOGAT2MGAT2 | |
| SCHEMBL4729847 | 0.77 | MOGAT2 (0.46) | CNR2CCR2KCNH2DRD3MOGAT2 | |
| SCHEMBL4778150 | 0.76 | PGR (0.50) | CNR2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |