Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | UQCRB | P14927 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725768 | 0.88 | MAPT (0.51) | CRHBPCRHR2ALDH1A1MAPTKMT2A | |
| SCHEMBL4729811 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL4727610 | 0.87 | UCHL1 (0.51) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL4728012 | 0.87 | CES1 (0.48) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL4726510 | 0.87 | CNR2 (0.49) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL4728036 | 0.85 | DRD3 (0.42) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL4730511 | 0.85 | FFAR1 (0.44) | ALDH1A1MEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL4725454 | 0.85 | DRD3 (0.57) | ALDH1A1MEN1MAPTKMT2ALMNA | |
| SCHEMBL4725306 | 0.84 | POLB (0.54) | CRHBPCRHR2ALDH1A1MEN1MAPT | |
| SCHEMBL4728980 | 0.84 | DRD3 (0.42) | ALDH1A1MEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |