Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730991 | 0.91 | APOBEC3A (0.33) | JAK2TP53 | |
| SCHEMBL4730432 | 0.87 | NPC1 (0.38) | SLC6A9IRAK4 | |
| SCHEMBL4730446 | 0.86 | KDM4E (0.38) | TP53RXFP1 | |
| SCHEMBL4732771 | 0.83 | APOBEC3A (0.34) | JAK2TP53 | |
| SCHEMBL14223294 | 0.82 | NPC1 (0.37) | SLC6A9IRAK4TP53RXFP1 | |
| SCHEMBL4732780 | 0.80 | NTRK1 (0.34) | — | |
| SCHEMBL4731095 | 0.80 | S1PR1 (0.36) | IRAK4 | |
| SCHEMBL4728761 | 0.79 | SLC6A9 (0.33) | SLC6A9 | |
| SCHEMBL14291286 | 0.79 | IKBKB (0.33) | SLC6A9 | |
| SCHEMBL4727903 | 0.79 | MAPT (0.39) | TP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | claimed |
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |