Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731314 | 0.93 | APOBEC3A (0.33) | APOBEC3AAPOBEC3GABL1BCRLMNA | |
| SCHEMBL4731374 | 0.93 | NTRK1 (0.34) | NTRK1ALOX5APFEN1ALDH1A1 | |
| SCHEMBL4730991 | 0.89 | APOBEC3A (0.33) | NTRK1APOBEC3AAPOBEC3GABL1LMNA | |
| SCHEMBL4731297 | 0.86 | TP53 (0.34) | ALDH1A1 | |
| SCHEMBL4731299 | 0.84 | APOBEC3A (0.35) | NTRK1APOBEC3AAPOBEC3GABL1 | |
| SCHEMBL2157820 | 0.84 | NTRK1 (0.45) | NTRK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4732771 | 0.83 | APOBEC3A (0.34) | NTRK1APOBEC3AAPOBEC3GABL1LMNA | |
| SCHEMBL4732555 | 0.83 | APOBEC3A (0.34) | NTRK1APOBEC3AAPOBEC3GABL1SMN1; SMN2 | |
| SCHEMBL4730446 | 0.82 | KDM4E (0.38) | — | |
| SCHEMBL4728477 | 0.80 | SLC6A9 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | claimed |
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |