Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731545 | 0.92 | ALDH1A1 (0.46) | HPGDS | |
| SCHEMBL4780927 | 0.92 | ALDH1A1 (0.46) | HPGDS | |
| SCHEMBL4729592 | 0.85 | PDGFRB (0.42) | HPGDS | |
| SCHEMBL5511161 | 0.82 | MGAM (0.49) | HPGDS | |
| SCHEMBL6093635 | 0.79 | CNR2 (0.55) | — | |
| SCHEMBL5505975 | 0.77 | MEN1 (0.58) | — | |
| SCHEMBL4730657 | 0.77 | MAPT (0.35) | — | |
| SCHEMBL4730336 | 0.77 | ALDH1A1 (0.36) | — | |
| SCHEMBL5504502 | 0.76 | ABCG2 (0.50) | — | |
| SCHEMBL4729401 | 0.76 | MAOA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |