Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726425 | 1.00 | MAOA (0.47) | MAOAMAOBNNMTMKNK1MKNK2 | |
| SCHEMBL6093635 | 0.80 | CNR2 (0.55) | MAOAMAOBCNR2LMNAMEN1 | |
| SCHEMBL4728653 | 0.76 | HPGDS (0.54) | — | |
| SCHEMBL4731545 | 0.76 | ALDH1A1 (0.46) | — | |
| SCHEMBL4780927 | 0.76 | ALDH1A1 (0.46) | — | |
| SCHEMBL4729592 | 0.75 | PDGFRB (0.42) | CNR2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4729406 | 0.75 | PKM (0.46) | CNR2LMNAKDM4EMEN1MAPT | |
| SCHEMBL4728510 | 0.75 | PKM (0.46) | CNR2LMNAKDM4EMEN1MAPT | |
| SCHEMBL5504502 | 0.75 | ABCG2 (0.50) | MAOBCNR2MEN1KMT2A | |
| SCHEMBL1769995 | 0.74 | TSHR (0.56) | LMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |