Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729527 | 0.91 | PPARD (0.49) | PPARDPPARAMAOBFFAR1FFAR4 | |
| SCHEMBL16914905 | 0.88 | PPARD (0.54) | PPARDPPARAMAOBFFAR1PPARG | |
| SCHEMBL12477083 | 0.85 | PTPN1 (0.40) | PPARDPPARAPPARGSMN1; SMN2 | |
| SCHEMBL4727921 | 0.85 | FFAR1 (0.53) | PPARDPPARAFFAR1FFAR4PPARG | |
| SCHEMBL15543422 | 0.84 | LMNA (0.49) | — | |
| SCHEMBL12477097 | 0.83 | FFAR1 (0.49) | PPARDPPARAMAOBFFAR1FFAR4 | |
| SCHEMBL4727711 | 0.83 | PPARD (0.67) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL15542947 | 0.83 | KMT2A (0.46) | SMN1; SMN2 | |
| SCHEMBL15543166 | 0.82 | FKBP1A (0.51) | SMN1; SMN2 | |
| SCHEMBL15543282 | 0.81 | MDH1 (0.45) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| EP-2658851-A1 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Cadila Healthcare Limited (IN) | 2013-11-06 | — | — | EP | disclosed |
| WO-2012090220-A1 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2012-07-05 | — | — | WO | disclosed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |