Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MDH1 | P40925 | 1/20 | 0.46 |
| ▸ | MDH2 | P40926 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15543282 | 0.88 | MDH1 (0.45) | ALDH1A1MAPTMDH1MDH2USP2 | |
| SCHEMBL15543059 | 0.86 | EPHX2 (0.43) | ALDH1A1POLBKMT2AMAPTKEAP1 | |
| SCHEMBL15543370 | 0.83 | MDH1 (0.40) | ALDH1A1KMT2AMAPTSMN1; SMN2MDH1 | |
| SCHEMBL15543206 | 0.83 | L3MBTL1 (0.51) | SMN1; SMN2MDH1MDH2ENPP2KDM4E | |
| SCHEMBL4729104 | 0.82 | PPARD (0.52) | SMN1; SMN2 | |
| SCHEMBL12476505 | 0.80 | FAAH (0.43) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15543281 | 0.80 | FKBP1A (0.54) | FKBP1AALDH1A1POLBKMT2AMAPT | |
| SCHEMBL15543283 | 0.80 | FKBP1A (0.54) | FKBP1AALDH1A1POLBKMT2AMAPT | |
| SCHEMBL15543249 | 0.80 | MAPT (0.61) | ALDH1A1POLBKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15543164 | 0.79 | FKBP1A (0.55) | FKBP1AALDH1A1POLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864309-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | Cadila Healthcare Limited (IN) | 2015-04-29 | — | — | EP | disclosed |
| WO-2014002105-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2014-01-03 | — | — | WO | disclosed |