Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDH1 | P40925 | 1/20 | 0.45 |
| ▸ | MDH2 | P40926 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15543325 | 0.91 | MDH1 (0.46) | MDH1MDH2ENPP2USP2ALDH1A1 | |
| SCHEMBL15543665 | 0.90 | FKBP1A (0.47) | ENPP2USP2ALDH1A1GHSRLMNA | |
| SCHEMBL15543166 | 0.88 | FKBP1A (0.51) | MDH1MDH2ENPP2USP2ALDH1A1 | |
| SCHEMBL15543111 | 0.88 | GHSR (0.52) | ALDH1A1GHSR | |
| SCHEMBL15543370 | 0.86 | MDH1 (0.40) | MDH1MDH2ENPP2ALDH1A1YAP1 | |
| SCHEMBL15542804 | 0.84 | GPR183 (0.48) | USP2ALDH1A1GHSRLMNAMAPT | |
| SCHEMBL15543206 | 0.82 | L3MBTL1 (0.51) | MDH1MDH2ENPP2HRH3SLC6A5 | |
| SCHEMBL4729104 | 0.81 | PPARD (0.52) | MAOB | |
| SCHEMBL16468578 | 0.81 | MDH1 (0.48) | MDH1MDH2ENPP2USP2ALDH1A1 | |
| SCHEMBL15543323 | 0.81 | MDH1 (0.48) | MDH1MDH2ENPP2USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864309-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | Cadila Healthcare Limited (IN) | 2015-04-29 | — | — | EP | claimed |
| WO-2014002105-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2014-01-03 | — | — | WO | claimed |
| EP-2864309-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | Cadila Healthcare Limited (IN) | 2015-04-29 | — | — | EP | disclosed |
| WO-2014002105-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2014-01-03 | — | — | WO | disclosed |