Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732188 | 0.84 | TSHR (0.35) | ALDH1A1CA2CYP3A4MAPK1LMNA | |
| SCHEMBL4732244 | 0.82 | TSHR (0.34) | ALDH1A1CA2CYP3A4MAPK1 | |
| SCHEMBL4783446 | 0.81 | TSHR (0.33) | CA2CYP3A4MAPK1CTSK | |
| SCHEMBL4731966 | 0.81 | MAPK1 (0.42) | ALDH1A1MAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL8923209 | 0.77 | ALDH1A1 (0.43) | ALDH1A1CA2CYP3A4MAPK1LMNA | |
| SCHEMBL8031491 | 0.75 | CA2 (0.45) | ALDH1A1CA2CYP3A4MAPK1PRSS1 | |
| SCHEMBL4729114 | 0.74 | ALDH1A1 (0.41) | ALDH1A1CA2CYP3A4MAPK1LMNA | |
| SCHEMBL4729107 | 0.74 | ALDH1A1 (0.41) | ALDH1A1CA2CYP3A4MAPK1LMNA | |
| SCHEMBL8923215 | 0.74 | ALDH1A1 (0.45) | ALDH1A1CA2CYP3A4MAPK1LMNA | |
| SCHEMBL27619467 | 0.72 | TSHR (0.43) | ALDH1A1CA2CYP3A4MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080250739-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-10-16 | — | — | US | disclosed |
| WO-2008057705-A1 | FOAMED PLASTIC STRUCTURES | NOVA CHEMICALS INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-6093781-A | STYRENIC MONOMER COPOLYMERIZED WITH NEW CLASS OF INITIATORS THAT CONTAIN BOTH A COPOLYMERIZABLE DOUBLE BOND AND AN ORGANIC PEROXIDE MOIETY; HIGH SPEED THERMOFORMING | THE DOW CHEMICAL COMPANY (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0785964-B1 | NON-LINEAR STYRENIC POLYMER-BASED FOAMS | DOW CHEMICAL CO (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5830924-A | LOW DENSITY CLOSED CELL, BLOWING AGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0785957-B1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | DOW CHEMICAL CO (US) | 1998-05-20 | — | — | EP | disclosed |
| EP-0785957-A1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| EP-0785964-A1 | NON-LINEAR STYRENIC POLYMER-BASED FOAMS | THE DOW CHEMICAL COMPANY (US) | 1997-07-30 | — | — | EP | disclosed |
| WO-1996011962-A1 | NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1996-04-25 | — | — | WO | disclosed |
| WO-1996011970-A1 | NON-LINEAR STYRENIC POLYMER-BASED FOAMS | THE DOW CHEMICAL COMPANY (US) | 1996-04-25 | — | — | WO | disclosed |