SCHEMBL4783446

SCHEMBL4783446

CCCCC(CC)CC(=CC(=O)O)C(=O)OOOC(C)(C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
RECQL P46063 1/20 0.33
CYP3A4 P08684 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA2 P00918 3/20 0.31
MAPK1 P28482 1/20 0.31
CTSK P43235 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4732188 0.89 TSHR (0.35) TSHRRECQLCYP3A4ATMTDP1
SCHEMBL4732244 0.87 TSHR (0.34) TSHRRECQLCYP3A4ATMTDP1
SCHEMBL4729112 0.81 ALDH1A1 (0.38) CYP3A4CA2MAPK1CTSK
SCHEMBL9241981 0.81 LMNA (0.35) TSHRRECQLTDP1
SCHEMBL5001491 0.80
SCHEMBL27619467 0.76 TSHR (0.43) TSHRRECQLCYP3A4ATMTDP1
SCHEMBL450703 0.75 TSHR (0.52) TSHRRECQLCYP3A4ATMTDP1
SCHEMBL9242600 0.75 TSHR (0.53) TSHRRECQLCYP3A4ATMTDP1
SCHEMBL2250221 0.74 CA2 (0.43) TSHRRECQLCYP3A4ATMTDP1
SCHEMBL183765 0.74 CA2 (0.43) TSHRRECQLCYP3A4ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080250739-A1 FOAMED PLASTIC STRUCTURES NOVA CHEMICALS INC. (US) 2008-10-16 US disclosed
WO-2008057705-A1 FOAMED PLASTIC STRUCTURES NOVA CHEMICALS INC. (US) 2008-05-15 WO disclosed
US-6093781-A STYRENIC MONOMER COPOLYMERIZED WITH NEW CLASS OF INITIATORS THAT CONTAIN BOTH A COPOLYMERIZABLE DOUBLE BOND AND AN ORGANIC PEROXIDE MOIETY; HIGH SPEED THERMOFORMING THE DOW CHEMICAL COMPANY (US) 2000-07-25 US disclosed
EP-0785964-B1 NON-LINEAR STYRENIC POLYMER-BASED FOAMS DOW CHEMICAL CO (US) 1999-04-14 EP disclosed
US-5830924-A LOW DENSITY CLOSED CELL, BLOWING AGENTS THE DOW CHEMICAL COMPANY (US) 1998-11-03 US disclosed
EP-0785957-B1 NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM DOW CHEMICAL CO (US) 1998-05-20 EP disclosed
EP-0785957-A1 NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1997-07-30 EP disclosed
WO-1996011962-A1 NON-LINEAR STYRENIC POLYMER COMPOSITIONS AND ARTICLES PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1996-04-25 WO disclosed