Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 7/20 | 0.49 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552481 | 0.81 | FABP4 (0.68) | FABP4FABP5MAOAMAOBACHE | |
| SCHEMBL4552166 | 0.81 | FABP4 (0.64) | FABP4FABP5MAOAMAOBACHE | |
| SCHEMBL18014692 | 0.81 | FABP4 (0.51) | FABP4FABP5MAOAMAOBACHE | |
| SCHEMBL6230810 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL14292496 | 0.79 | FABP4 (0.58) | FABP4FABP5MAOAMAOBACHE | |
| SCHEMBL6338101 | 0.79 | MAOA (0.69) | FABP4FABP5MAOAMAOBACHE | |
| SCHEMBL10063551 | 0.79 | MAOA (0.69) | FABP4FABP5MAOAMAOBACHE | |
| SCHEMBL5658338 | 0.79 | MAOA (0.69) | FABP4FABP5MAOAMAOBACHE | |
| SCHEMBL5181736 | 0.79 | MAOA (0.69) | FABP4FABP5MAOAMAOBACHE | |
| SCHEMBL4726204 | 0.78 | FABP4 (0.59) | FABP4FABP5MAOAMAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |