Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730901 | 0.84 | ALDH1A1 (0.46) | LMNAMAPTPKMALDH1A1KMT2A | |
| SCHEMBL29042707 | 0.83 | LMNA (0.56) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL4732303 | 0.81 | MAPT (0.47) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL4733846 | 0.80 | UTS2R (0.40) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4731994 | 0.80 | ACHE (0.39) | LMNAALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL4731826 | 0.80 | LMNA (0.51) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL1825138 | 0.80 | KMT2A (0.47) | LMNAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4733624 | 0.79 | VDR (0.42) | LMNAPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL2539962 | 0.77 | LMNA (0.51) | LMNAMAPTPOLBPKMALDH1A1 | |
| SCHEMBL25138830 | 0.76 | LMNA (0.67) | LMNAMAPTPOLBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008054155-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |