Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729274 | 0.81 | LMNA (0.51) | MAPTPKMPOLBLMNAKDM4E | |
| SCHEMBL4731661 | 0.81 | CA1 (0.42) | PKMTSHRKMT2APTGS2ALDH1A1 | |
| SCHEMBL13877485 | 0.80 | MAPT (0.51) | MAPTPKMPOLBLMNAKDM4E | |
| SCHEMBL1824697 | 0.76 | ENPP3 (0.36) | MAPTPKMPOLBKDM4ECYP3A4 | |
| SCHEMBL4731665 | 0.76 | ALDH1A1 (0.37) | PTGS2GAAALDH1A1 | |
| SCHEMBL4731943 | 0.76 | ADRB2 (0.35) | CYP3A4TSHRHIF1AHSD17B10PTGS2 | |
| SCHEMBL19717861 | 0.75 | KMT2A (0.37) | MAPTPOLBLMNAKDM4ECYP3A4 | |
| SCHEMBL4731570 | 0.73 | GRIA4 (0.43) | MAPTLMNAKDM4ECYP3A4CYP2C9 | |
| SCHEMBL15019127 | 0.73 | MEN1 (0.43) | MAPTPKMPOLBLMNAKDM4E | |
| SCHEMBL8069881 | 0.72 | LMNA (0.50) | MAPTPKMPOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008054155-A1 | METHOD FOR THE PREPARATION OF OPTICALLY ACTIVE 2-SULFONYLOXY-1-PHENYLETHANOL DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-05-08 | — | — | WO | disclosed |