Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 16/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 16/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215082 | 0.87 | HPGDS (0.42) | — | |
| SCHEMBL8212845 | 0.87 | ALDH1A1 (0.42) | PDGFRBPDGFRAGRM1 | |
| SCHEMBL4729407 | 0.87 | PDGFRB (0.48) | PDGFRBPDGFRAGRM1 | |
| SCHEMBL8211978 | 0.84 | GRM1 (0.40) | GRM1 | |
| SCHEMBL8215059 | 0.83 | GRM1 (0.40) | GRM1 | |
| SCHEMBL8215665 | 0.79 | RXRA (0.36) | GRM1 | |
| SCHEMBL4729426 | 0.73 | ALDH1A1 (0.49) | PDGFRBPDGFRAGRM1 | |
| SCHEMBL4728861 | 0.73 | HPGDS (0.46) | GRM1 | |
| SCHEMBL8215134 | 0.73 | ITK (0.35) | GRM1 | |
| SCHEMBL8219547 | 0.71 | CNR2 (0.35) | GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |