Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728434 | 0.87 | L3MBTL1 (0.39) | CNR1CNR2L3MBTL1 | |
| SCHEMBL4779852 | 0.85 | KDM4E (0.48) | SMN1; SMN2KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL4782013 | 0.83 | PDE4B (0.45) | SMN1; SMN2KDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL4730476 | 0.81 | CNR1 (0.45) | KDM4EMAPTMEN1KMT2ACNR1 | |
| Hydrochloric Acid SCHEMBL4783070 | 0.79 | CNR1 (0.52) | LMNAMAPTNPSR1CNR1CNR2 | |
| SCHEMBL4728429 | 0.79 | MARS1 (0.35) | KDM4ELMNAMAPTNPSR1MEN1 | |
| SCHEMBL4729374 | 0.79 | CNR2 (0.36) | KDM4ELMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL4728229 | 0.77 | KDM4E (0.47) | KDM4EMAPTMEN1KMT2ACNR1 | |
| SCHEMBL4728284 | 0.77 | CNR2 (0.38) | NPSR1ALDH1A1CNR1CNR2 | |
| SCHEMBL4727572 | 0.77 | CNR1 (0.49) | KDM4EMAPTMEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |