Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | POR | P16435 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727318 | 0.87 | ALDH1A1 (0.43) | CYP11B2ALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL4726095 | 0.85 | PPARG (0.46) | PPARGALDH1A1L3MBTL1MAOBHPGD | |
| SCHEMBL4726892 | 0.85 | TDP2 (0.46) | CYP11B2ALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL4728259 | 0.85 | CYP11B2 (0.40) | CYP11B2ALDH1A1L3MBTL1MAPTTDP1 | |
| SCHEMBL4726625 | 0.85 | CYP11B2 (0.40) | CYP11B2ALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL4729580 | 0.83 | CYP11B2 (0.51) | CYP11B2ALDH1A1L3MBTL1MAPTKDM4E | |
| SCHEMBL4784487 | 0.82 | ALDH1A1 (0.40) | PPARGALDH1A1MALT1L3MBTL1MAPT | |
| SCHEMBL4726123 | 0.78 | TDP2 (0.41) | CYP11B2ALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL4730197 | 0.78 | MAPK1 (0.40) | CYP11B2ALDH1A1L3MBTL1MAPTTDP1 | |
| SCHEMBL4729677 | 0.76 | CYP1A1 (0.41) | CYP1A1PPARGALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |