Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801378 | 0.81 | KDM4E (0.39) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL4802225 | 0.66 | KMT2A (0.41) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL4795055 | 0.64 | KMT2A (0.39) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL4734556 | 0.63 | KCNK2 (0.41) | ALDH1A1PTGDR2 | |
| SCHEMBL4798095 | 0.62 | HTR2C (0.39) | ALDH1A1HTTHTR2AHTR2CSMN1; SMN2 | |
| SCHEMBL5531315 | 0.61 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL27658769 | 0.60 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL2060095 | 0.58 | PKM (0.62) | PKMMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4705429 | 0.58 | GAA (0.61) | PKMMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4704361 | 0.58 | GAA (0.61) | PKMMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |