Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 10/20 | 0.37 |
| ▸ | HTR2C | P28335 | 10/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4802225 | 0.99 | KMT2A (0.41) | KMT2AKDM4EMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4798095 | 0.85 | HTR2C (0.39) | ALDH1A1HTR2AHTR2CSMN1; SMN2 | |
| SCHEMBL4732186 | 0.71 | HTT (0.36) | KMT2AMEN1ALDH1A1L3MBTL1GAA | |
| SCHEMBL4732586 | 0.70 | HTT (0.38) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL4795053 | 0.70 | ALDH1A1 (0.38) | KMT2AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL4802221 | 0.69 | ALDH1A1 (0.38) | KMT2AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL4730085 | 0.69 | KMT2A (0.41) | KMT2AKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL4730155 | 0.69 | CNR2 (0.39) | GAALMNA | |
| SCHEMBL4732243 | 0.68 | CNR2 (0.39) | ALDH1A1GAALMNA | |
| SCHEMBL4798089 | 0.67 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |