Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730191 | 0.72 | GAA (0.42) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL5655023 | 0.72 | ALDH1A1 (0.42) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL5230947 | 0.71 | ALDH1A1 (0.44) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL5653946 | 0.67 | KDM4E (0.48) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL5653948 | 0.67 | KDM4E (0.48) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL5396883 | 0.65 | GAA (0.47) | GAAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL1870853 | 0.64 | LMNA (0.59) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL12633216 | 0.64 | LMNA (0.59) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL1710167 | 0.64 | LMNA (0.59) | GAAMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL5078683 | 0.62 | LMNA (0.55) | MAPTALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047210-A2 | COMPOUNDS DERIVED FROM 1 -ETHYL-4,5-DIAMINO-PYRAZOLE AND THEIR USE FOR OXIDATIVE DYEING OF KERATIN FIBRES | KEMON S.P.A. (IT) | 2008-04-24 | — | — | WO | disclosed |