Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13141391 | 0.88 | KMT2A (0.35) | KMT2AALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL11389305 | 0.84 | FABP4 (0.37) | KMT2AALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL632529 | 0.84 | KMT2A (0.36) | KMT2AALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL160615 | 0.81 | KMT2A (0.54) | KMT2AALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL13141386 | 0.80 | CTSS (0.36) | KMT2AALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL17067451 | 0.79 | LMNA (0.33) | KMT2AALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL28220747 | 0.77 | KMT2A (0.36) | KMT2AALDH1A1NPC1MEN1CYP1A2 | |
| SCHEMBL632902 | 0.76 | PKM (0.49) | ALDH1A1NPC1POLBL3MBTL1RAB9A | |
| SCHEMBL6979582 | 0.76 | KMT2A (0.43) | KMT2AALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL5725289 | 0.75 | POLB (0.46) | KMT2AALDH1A1NPC1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |