Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491274 | 1.00 | NPC1 (0.56) | NPC1RAB9AMTNR1AMTNR1BTRPV1 | |
| SCHEMBL20307881 | 0.90 | TRPV1 (0.49) | NPC1RAB9ATRPV1 | |
| SCHEMBL4798612 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BTRPV1ADRA2CSLC6A2 | |
| SCHEMBL16212524 | 0.79 | ADRA2C (0.60) | ADRA2CSLC6A2HTR2CSLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL1504932 | 0.78 | SIGMAR1 (0.60) | ADRA2CSLC6A2HTR2CSLC6A4OPRM1 | |
| SCHEMBL8212125 | 0.76 | ADRA2C (0.47) | NPC1RAB9ATRPV1ADRA2CSLC6A2 | |
| SCHEMBL6495378 | 0.76 | MTNR1A (0.67) | MTNR1AMTNR1B | |
| SCHEMBL1491247 | 0.76 | ADRA2C (0.65) | NPC1RAB9AADRA2CSLC6A2HTR2C | |
| SCHEMBL4730665 | 0.76 | MEN1 (0.53) | MTNR1ATRPV1HTT | |
| SCHEMBL8469429 | 0.76 | ADRA2C (0.65) | NPC1RAB9AADRA2CSLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120349246-A | Preparation method of cinacalcet hydrochloride and intermediate thereof | 上海博志研新药物研究有限公司 | 2025-07-22 | — | — | CN | disclosed |