Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16212524 | 0.75 | ADRA2C (0.60) | ADRA2CSLC6A2HTR2CSLC6A4OPRM1 | |
| SCHEMBL4730665 | 0.74 | MEN1 (0.53) | MTNR1ATRPV1ALDH1A1POLBHTT | |
| Hydrochloric Acid SCHEMBL1504932 | 0.74 | SIGMAR1 (0.60) | ADRA2CSLC6A2HTR2CSLC6A4OPRM1 | |
| SCHEMBL1491274 | 0.74 | NPC1 (0.56) | MTNR1ATRPV1ADRA2CSLC6A2HTR2C | |
| SCHEMBL31663470 | 0.74 | NPC1 (0.56) | MTNR1ATRPV1ADRA2CSLC6A2HTR2C | |
| SCHEMBL3804054 | 0.73 | MTNR1A (0.42) | MTNR1ATRPV1ADRA2CSLC6A2HTR2C | |
| SCHEMBL2787173 | 0.73 | CASR (0.55) | CNR2ADRA2CSLC6A2HTR2CSLC6A4 | |
| SCHEMBL6076911 | 0.73 | TRPV1 (0.67) | MTNR1ATRPV1ALDH1A1POLBHTT | |
| SCHEMBL2874457 | 0.72 | MEN1 (0.44) | MTNR1ATRPV1ADRA2CSLC6A2HTR2C | |
| SCHEMBL2787298 | 0.72 | MEN1 (0.44) | MTNR1ATRPV1ADRA2CSLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128388-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF CINACALCET | AUROBINDO PHARMA LIMITED (IN) | 2010-11-11 | — | — | WO | disclosed |