Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 7/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13528430 | 0.90 | CREBBP (0.56) | CREBBPHDAC8ALDH1A1LMNAMAPK1 | |
| SCHEMBL7160525 | 0.88 | CREBBP (0.61) | CREBBPHDAC8ALDH1A1MAPK1HDAC1 | |
| SCHEMBL4734254 | 0.87 | ALDH1A1 (0.57) | CREBBPHDAC8ALDH1A1LMNAMAPK1 | |
| SCHEMBL966146 | 0.85 | MAOB (0.52) | CREBBPLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL641868 | 0.84 | CREBBP (0.64) | CREBBPHDAC8LMNAHDAC1HDAC6 | |
| SCHEMBL4001489 | 0.84 | LMNA (0.44) | CREBBPALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL7962680 | 0.83 | CREBBP (0.62) | CREBBPHDAC8ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14279020 | 0.82 | TSHR (0.52) | ALDH1A1LMNAMAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5334076 | 0.81 | LMNA (0.54) | CREBBPLMNAKMT2ASMN1; SMN2HTT | |
| SCHEMBL5312956 | 0.81 | CA12 (0.68) | LMNAMEN1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778442-A | Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-112759683-A | Olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-111057169-B | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-111057168-B | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-112778442-A | Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-112759683-A | Olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111057169-A | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-04-24 | — | — | CN | disclosed |
| WO-2008054454-A2 | NITROGEN-CONTAINING HETEROCYCLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF AS ANTIVIRAL AGENTS | TRANSTECH PHARMA, INC. (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20070219239-A1 | Nitrogen-containing heterocycle derivatives, pharmaceutical compositions, and methods of use thereof as antiviral agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-09-20 | — | — | US | disclosed |
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219239-A1 | Nitrogen-containing heterocycle derivatives, pharmaceutical compositions, and methods of use thereof as antiviral agents | NUDT1, PNP, NME2 | CREBBP 2496/4885HDAC8 1609/4885ALDH1A1 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.