Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213312 | 0.85 | TRPM5 (0.37) | CNR1TRPM5MAPTSMN1; SMN2NPC1 | |
| SCHEMBL2136784 | 0.79 | MGAM (0.50) | TRPM5MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL2136780 | 0.79 | MGAM (0.50) | TRPM5MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL4731345 | 0.77 | P2RX7 (0.49) | MAPTKDM4ELMNARAB9AHTT | |
| SCHEMBL4728893 | 0.76 | GRM1 (0.51) | CNR1MAPTKDM4ESMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL4728933 | 0.76 | P2RX7 (0.48) | MAPTKDM4ELMNARAB9AHTT | |
| Hydrochloric Acid SCHEMBL4727017 | 0.75 | GRM1 (0.50) | CNR1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL16278329 | 0.74 | TRPM5 (0.44) | TRPM5MAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL16278689 | 0.74 | TRPM5 (0.54) | TRPM5MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL16283865 | 0.74 | TRPM5 (0.44) | TRPM5MAPTKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |