Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13357307 | 1.00 | NOS3 (0.43) | NOS3NOS2GABRPGABRDGABRA1 | |
| SCHEMBL13699050 | 0.79 | MASP2 (0.41) | NOS3NOS2GABRPGABRDGABRA1 | |
| SCHEMBL12749109 | 0.79 | NOS2 (0.46) | NOS3NOS2GABRPGABRDGABRA1 | |
| SCHEMBL12678596 | 0.79 | NOS2 (0.46) | NOS3NOS2GABRPGABRDGABRA1 | |
| SCHEMBL2477542 | 0.78 | HTR2A (0.56) | NOS3NOS2GABRPGABRDGABRA1 | |
| SCHEMBL10193818 | 0.78 | HDAC1 (0.36) | HDAC1HDAC6 | |
| SCHEMBL7899522 | 0.77 | NOS3 (0.43) | NOS3NOS2GABRPGABRDGABRA1 | |
| SCHEMBL621387 | 0.77 | CHRNB2 (0.58) | NOS3NOS2GABRPGABRDGABRA1 | |
| SCHEMBL12357203 | 0.76 | NFE2L2 (0.45) | KDM4ENPC1RAB9A | |
| SCHEMBL2600298 | 0.76 | NFE2L2 (0.45) | KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064054-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |