Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510873 | 0.79 | ABCG2 (0.56) | MEN1KMT2AP2RX7 | |
| SCHEMBL4729642 | 0.76 | CNR2 (0.46) | CNR2FAAHMEN1KMT2AP2RX7 | |
| SCHEMBL6092329 | 0.74 | KMT2A (0.48) | MEN1KMT2AP2RX7CYP17A1CYP19A1 | |
| SCHEMBL4728169 | 0.73 | TSHR (0.56) | CYP3A4MEN1KMT2AP2RX7CYP17A1 | |
| SCHEMBL1769995 | 0.73 | TSHR (0.56) | CYP3A4MEN1KMT2AP2RX7CYP17A1 | |
| SCHEMBL5509233 | 0.72 | ABCG2 (0.52) | MEN1KMT2A | |
| SCHEMBL4728510 | 0.72 | PKM (0.46) | CNR2MEN1KMT2A | |
| SCHEMBL4729401 | 0.72 | MAOA (0.47) | CNR2MEN1KMT2A | |
| SCHEMBL4729406 | 0.72 | PKM (0.46) | CNR2MEN1KMT2A | |
| SCHEMBL4726425 | 0.72 | MAOA (0.47) | CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |