Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732085 | 0.76 | TGM2 (0.42) | CNR2FAAHKMT2AMEN1P2RX7 | |
| SCHEMBL4728914 | 0.74 | RAB9A (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL4731777 | 0.74 | RAB9A (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL4726956 | 0.73 | MEN1 (0.42) | CNR2ALDH1A1FAAHKMT2AMEN1 | |
| SCHEMBL6092524 | 0.72 | P2RX7 (0.50) | CNR2ALDH1A1SMN1; SMN2FAAHKMT2A | |
| SCHEMBL6092329 | 0.72 | KMT2A (0.48) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL6092078 | 0.72 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KDM4EHTTP2RX7 | |
| SCHEMBL5510873 | 0.72 | ABCG2 (0.56) | SMN1; SMN2KMT2AMEN1HTTP2RX7 | |
| SCHEMBL4729401 | 0.72 | MAOA (0.47) | CNR2KMT2AMEN1KDM4E | |
| SCHEMBL4726425 | 0.72 | MAOA (0.47) | CNR2KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |