Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216865 | 0.85 | RAB9A (0.36) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL5510876 | 0.79 | JUN (0.60) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL4729644 | 0.76 | CNR2 (0.46) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL8068014 | 0.74 | JUN (0.51) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL6092331 | 0.74 | JUN (0.51) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL8077622 | 0.73 | MAPT (0.56) | MEN1KMT2AMAPTCYP17A1CYP19A1 | |
| SCHEMBL1769996 | 0.73 | MAPT (0.56) | MEN1KMT2AMAPTCYP17A1CYP19A1 | |
| SCHEMBL16052805 | 0.72 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL5509239 | 0.72 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL4728511 | 0.72 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |