Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215908 | 0.85 | CNR2 (0.36) | CNR2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28357086 | 0.76 | KDM4E (0.49) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL4732088 | 0.76 | MEN1 (0.45) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL4728916 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL4726961 | 0.73 | KMT2A (0.43) | CNR2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6092527 | 0.72 | HSD11B1 (0.54) | CNR2MEN1KMT2AKDM4EHPGD | |
| SCHEMBL8068014 | 0.72 | JUN (0.51) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL6092331 | 0.72 | JUN (0.51) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL6092082 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL4726429 | 0.72 | LMNA (0.51) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |