Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731449 | 0.76 | FFAR4 (0.35) | FFAR4IDO1ALDH1A1 | |
| SCHEMBL4730728 | 0.76 | BACE1 (0.35) | FFAR4IDO1ALDH1A1 | |
| SCHEMBL4733982 | 0.71 | HTR2A (0.35) | SRD5A1 | |
| SCHEMBL4732184 | 0.69 | MEN1 (0.39) | TYMS | |
| SCHEMBL4732823 | 0.66 | TRPV4 (0.34) | — | |
| SCHEMBL11003086 | 0.66 | CYP19A1 (0.32) | ALDH1A1 | |
| SCHEMBL186087 | 0.66 | KIF11 (0.48) | FFAR4IDO1ALDH1A1L3MBTL1 | |
| SCHEMBL29978561 | 0.66 | KIF11 (0.48) | FFAR4IDO1ALDH1A1L3MBTL1 | |
| SCHEMBL185520 | 0.66 | ALDH1A1 (0.52) | FFAR4IDO1ALDH1A1 | |
| SCHEMBL4732626 | 0.65 | ATM (0.40) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |