Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | EIF4E | P06730 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341157 | 0.79 | NPC1 (0.53) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL14551142 | 0.76 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL6646512 | 0.74 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL12796868 | 0.74 | EIF4E (0.61) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL4795299 | 0.72 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL3342093 | 0.72 | MAPT (0.72) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL876387 | 0.71 | RAB9A (0.58) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL4732495 | 0.70 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8525187 | 0.69 | POLB (0.57) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3337680 | 0.69 | CA12 (0.62) | MAPTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052804-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-08 | — | — | WO | disclosed |