Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLRA1 | P23415 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732921 | 0.87 | KMT2A (0.49) | MEN1KMT2AALDH1A1KDM4EGLRA1 | |
| SCHEMBL4733076 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL4782911 | 0.77 | MEN1 (0.46) | MEN1KMT2AALDH1A1KDM4ETSHR | |
| SCHEMBL8809637 | 0.70 | GABRA1 (0.45) | KMT2AALDH1A1GLRA1TSHR | |
| SCHEMBL4673748 | 0.70 | LMNA (0.41) | MEN1KMT2AALDH1A1KDM4EGLRA1 | |
| SCHEMBL13886370 | 0.69 | MEN1 (0.49) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9729410 | 0.68 | KMT2A (0.76) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4730730 | 0.68 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10212529 | 0.68 | RXRA (0.46) | GLRA1SRD5A2RARGRXRAPPARG | |
| SCHEMBL8476886 | 0.68 | GLRA1 (0.48) | GLRA1SRD5A2TSHRRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052288-A1 | DITHIOLE COMPOUNDS AS COX INHIBITORS | NEURO THERAPEUTICS LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008052288-A1 | DITHIOLE COMPOUNDS AS COX INHIBITORS | NEURO THERAPEUTICS LIMITED (AU) | 2008-05-08 | — | — | WO | disclosed |