Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731336 | 0.93 | CNR2 (0.39) | CNR2NAMPTHTR7HTR1ADRD2 | |
| SCHEMBL4732339 | 0.91 | NAMPT (0.38) | CNR2NAMPT | |
| SCHEMBL4731657 | 0.86 | HTR1A (0.38) | NAMPTHTR7HTR1ADRD2HTR6 | |
| SCHEMBL4732731 | 0.86 | CNR2 (0.38) | CNR2HTR7HTR1ADRD2HTR6 | |
| SCHEMBL4729817 | 0.82 | TSHR (0.43) | CNR2KMT2A | |
| SCHEMBL4730503 | 0.81 | SMN1; SMN2 (0.47) | KMT2A | |
| SCHEMBL4733955 | 0.81 | CYP3A4 (0.46) | KMT2A | |
| SCHEMBL4735405 | 0.79 | HTR1A (0.39) | HTR7HTR1ADRD2HTR6MEN1 | |
| SCHEMBL4732619 | 0.78 | TAAR1 (0.43) | KMT2ATP53 | |
| SCHEMBL4732031 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |