Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 7/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | SFRP1 | Q8N474 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731073 | 0.89 | SFRP1 (0.35) | EPHX2DPP4DPP7KCNH2DPP8 | |
| SCHEMBL4732378 | 0.88 | CCR8 (0.45) | SFRP1CCR8 | |
| SCHEMBL4734140 | 0.87 | SFRP1 (0.45) | SFRP1 | |
| SCHEMBL4730501 | 0.85 | DPP4 (0.39) | EPHX2DPP4DPP7KCNH2DPP8 | |
| SCHEMBL4730634 | 0.84 | WNT3 (0.37) | DPP4DPP7KCNH2HDAC8SFRP1 | |
| SCHEMBL4732698 | 0.84 | GSTO1 (0.38) | DPP4DPP7KCNH2HDAC8ALDH1A1 | |
| SCHEMBL4732381 | 0.81 | CCR8 (0.45) | SFRP1CCR8 | |
| SCHEMBL4734145 | 0.80 | SFRP1 (0.45) | SFRP1 | |
| SCHEMBL4730846 | 0.79 | DPP4 (0.39) | EPHX2DPP4DPP7KCNH2DPP8 | |
| SCHEMBL4733107 | 0.74 | SFRP1 (0.43) | SFRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |