Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 7/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | WNT3 | P56703 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | CCR8 | P51685 | 2/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733498 | 0.89 | EPHX2 (0.40) | SFRP1EPHX2DPP4KCNH2DPP7 | |
| SCHEMBL4730634 | 0.84 | WNT3 (0.37) | SFRP1DPP4KCNH2DPP7WNT3 | |
| SCHEMBL4732378 | 0.78 | CCR8 (0.45) | SFRP1CCR8 | |
| SCHEMBL4734140 | 0.77 | SFRP1 (0.45) | SFRP1WNT3 | |
| SCHEMBL4730501 | 0.75 | DPP4 (0.39) | SFRP1EPHX2DPP4KCNH2DPP7 | |
| SCHEMBL4732698 | 0.74 | GSTO1 (0.38) | DPP4KCNH2DPP7ALDH1A1SMN1; SMN2 | |
| SCHEMBL4730889 | 0.72 | SFRP1 (0.48) | SFRP1WNT3HDAC8CCR8 | |
| SCHEMBL4732381 | 0.71 | CCR8 (0.45) | SFRP1CCR8 | |
| SCHEMBL4734145 | 0.71 | SFRP1 (0.45) | SFRP1WNT3 | |
| SCHEMBL4730846 | 0.70 | DPP4 (0.39) | SFRP1EPHX2DPP4KCNH2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |