SCHEMBL47338

SCHEMBL47338

Cc1nc(O)c2ccccc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.52
GPR3 P46089 1/20 0.48
PRNP P04156 1/20 0.46
TSHR P16473 1/20 0.46
MAPK10 P53779 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP1A2 P05177 2/20 0.45
ERN1 O75460 1/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
NUDT1 P36639 1/20 0.44
PDE10A Q9Y233 1/20 0.43
BACE1 P56817 1/20 0.42
NCF1 P14598 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoylenurea SCHEMBL29460047 0.77 KDM4E (0.45) LMNAHTTGPR3TSHRKMT2A
Benzoylenurea SCHEMBL1752723 0.77 KDM4E (0.45) LMNAHTTGPR3TSHRKMT2A
SCHEMBL196601 0.77 GPR3 (0.64) LMNAHTTGPR3PRNPTSHR
SCHEMBL266459 0.77 CYP1A2 (0.64) HTTGPR3MEN1KMT2ACYP1A2
SCHEMBL30199873 0.77 CYP1A2 (0.64) HTTGPR3MEN1KMT2ACYP1A2
SCHEMBL29461212 0.76 TDP1 (0.54) LMNAHTTGPR3PRNPTSHR
Ammonia Solution, Strong SCHEMBL2184448 0.76 GPR3 (0.61) LMNAHTTGPR3PRNPTSHR
SCHEMBL856788 0.76 TDP1 (0.54) LMNAHTTGPR3PRNPTSHR
SCHEMBL8284883 0.75 LMNA (0.47) LMNATSHRMEN1KMT2AALDH1A1
SCHEMBL29892219 0.75 CYP1A2 (0.41) LMNACYP1A2ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118090990-A Preparation method of stable isotope labeled hypnone internal standard reagent 谱同生物医药科技(常州)有限公司 2024-05-28 CN claimed
US-20230293565-A1 USE OF WNT/BETA-CATENIN PATHWAY INHIBITORS TO BLOCK REPLICATION OF SARS-COV-2 AND OTHER PATHOGENIC VIRUSES THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2023-09-21 US claimed
CN-116249520-A Blocking replication of SARS-COV-2 and other pathogenic viruses using WNT/beta-catenin pathway inhibitors 阿尔伯塔大学理事会 2023-06-09 CN claimed
EP-4188378-A1 USE OF WNT/BETA-CATENIN PATHWAY INHIBITORS TO BLOCK REPLICATION OF SARS-COV-2 AND OTHER PATHOGENIC VIRUSES The Governors of the University of Alberta (CA) 2023-06-07 EP claimed
WO-2022020967-A1 USE OF WNT/BETA-CATENIN PATHWAY INHIBITORS TO BLOCK REPLICATION OF SARS-COV-2 AND OTHER PATHOGENIC VIRUSES THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2022-02-03 WO claimed
US-20020040002-A1 Hydroxamic acids substituted by heterocycles useful for inhibition of tumor necrosis factor ZENECA LIMITED 2002-04-04 US claimed
US-6251913-B1 Hydroxamic acids substituted by heterocycles useful for inhibition of tumor necrosis factor ZENECA LIMITED (GB) 2001-06-26 US claimed
EP-0971895-A1 HYDROXAMIC ACIDS SUBSTITUTED BY HETEROCYCLES USEFUL FOR INHIBITION OF TUMOR NECROSIS FACTOR AstraZeneca AB (SE) 2000-01-19 EP claimed
WO-1998043959-A1 HYDROXAMIC ACIDS SUBSTITUTED BY HETEROCYCLES USEFUL FOR INHIBITION OF TUMOR NECROSIS FACTOR ZENECA LIMITED (GB) 1998-10-08 WO claimed
US-20260115285-A1 MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER TORAY INDUSTRIES, INC. (JP) 2026-04-30 US disclosed
EP-4582101-A1 MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER Toray Industries, Inc. (JP) 2025-07-09 EP disclosed
US-20250127907-A1 PARP INHIBITORS Stablix, Inc. 2025-04-24 US disclosed
WO-2024264072-A2 PARP INHIBITORS Stablix, Inc. (US) 2024-12-26 WO disclosed
US-20240239805-A1 AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES UNIVERSITY OF KANSAS 2024-07-18 US disclosed
CN-1050604-C Compound with antipsychotic effect MEIJI SEIKA KABUSHIKA KAISHA (JP) 2000-03-22 CN disclosed
EP-0971895-A1 HYDROXAMIC ACIDS SUBSTITUTED BY HETEROCYCLES USEFUL FOR INHIBITION OF TUMOR NECROSIS FACTOR AstraZeneca AB (SE) 2000-01-19 EP disclosed
WO-1998043959-A1 HYDROXAMIC ACIDS SUBSTITUTED BY HETEROCYCLES USEFUL FOR INHIBITION OF TUMOR NECROSIS FACTOR ZENECA LIMITED (GB) 1998-10-08 WO disclosed
US-5599815-A SIDE EFFECT REDUCTION MEIJI SEIKA KABUSHIKI KAISHA (JP) 1997-02-04 US disclosed
CN-1103534-A Compound with antipsychotic effect MEIJI SEIKA CO (JP) 1995-06-07 CN disclosed
EP-0635506-A1 COMPOUND WITH ANTIPSYCHOTIC EFFECT MEIJI SEIKA KABUSHIKI KAISHA (JP) 1995-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239805-A1 AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES AZI2, NISCH, TET2 LMNA 4831/4885HTT 1123/4885GPR3 3332/4885
US-20260115285-A1 MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER PARP11, PARP1, PARP14 LMNA 840/4885HTT 4580/4885GPR3 4102/4885
US-20020040002-A1 Hydroxamic acids substituted by heterocycles useful for inhibition of tumor necrosis factor MMP1, HCAR1, MMP13 LMNA 1557/4885HTT 2229/4885GPR3 1731/4885
US-20250127907-A1 PARP INHIBITORS PARP1, PARP2, PARP3 LMNA 462/4885HTT 1568/4885GPR3 2388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.