Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4737130 | 0.92 | NOTUM (0.37) | NOTUMP2RY14MDM2KDM4C | |
| SCHEMBL4737129 | 0.78 | ACACB (0.31) | NOTUM | |
| Hydrochloric Acid SCHEMBL23389304 | 0.73 | CYP11B2 (0.35) | ALDH1A1LMNAL3MBTL1BRD4ICMT | |
| SCHEMBL14786484 | 0.73 | CYP11B2 (0.35) | ALDH1A1LMNAL3MBTL1BRD4ICMT | |
| SCHEMBL4734703 | 0.72 | BRD4 (0.38) | ALDH1A1RXFP1BRD4 | |
| SCHEMBL13732305 | 0.72 | PKM (0.36) | LMNAL3MBTL1RXFP1BRD4 | |
| SCHEMBL13736015 | 0.72 | PKM (0.36) | LMNAL3MBTL1RXFP1BRD4 | |
| SCHEMBL13735175 | 0.72 | RXFP1 (0.36) | P2RY14LMNAL3MBTL1RXFP1BRD4 | |
| SCHEMBL13736133 | 0.72 | PKM (0.36) | LMNAL3MBTL1RXFP1BRD4 | |
| SCHEMBL4734075 | 0.71 | BRD4 (0.57) | NOTUMP2RY14ALDH1A1LMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |