Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733752 | 0.89 | ADAM17 (0.32) | CA2ADAM17 | |
| SCHEMBL4734177 | 0.89 | PPARA (0.31) | — | |
| SCHEMBL4738186 | 0.89 | CA12 (0.31) | CA2 | |
| SCHEMBL4737146 | 0.87 | TDP1 (0.36) | CA2ADAM17 | |
| SCHEMBL4736892 | 0.86 | CA2 (0.32) | CA2 | |
| SCHEMBL5066412 | 0.84 | MAOB (0.35) | CA2ADAM17 | |
| SCHEMBL4736195 | 0.80 | CA2 (0.33) | CA2 | |
| SCHEMBL4736774 | 0.80 | MEN1 (0.31) | CA2 | |
| SCHEMBL4735347 | 0.79 | ADAM17 (0.30) | ADAM17 | |
| SCHEMBL4737598 | 0.78 | ADAM17 (0.35) | ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979324-A2 | NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER'S DISEASE, NEURODEGENERATION AND DEMENTIA | Astra Zeneca AB (SE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |
| WO-2007058602-A2 | NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER’S DISEASE, NEURODEGENERATION AND DEMENTIA. | ASTRAZENECA AB (SE) | 2007-05-24 | — | — | WO | disclosed |