Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737598 | 0.91 | ADAM17 (0.35) | TDP1ADAM17MAOBPTPN1 | |
| SCHEMBL4734993 | 0.87 | CA2 (0.33) | ADAM17CA2 | |
| SCHEMBL4738186 | 0.85 | CA12 (0.31) | CA2CA12 | |
| SCHEMBL4733752 | 0.79 | ADAM17 (0.32) | ADAM17CA2 | |
| SCHEMBL4735347 | 0.78 | ADAM17 (0.30) | ADAM17 | |
| SCHEMBL4734177 | 0.77 | PPARA (0.31) | — | |
| SCHEMBL4736892 | 0.75 | CA2 (0.32) | CA2 | |
| SCHEMBL4736774 | 0.75 | MEN1 (0.31) | MEN1KMT2ACA2 | |
| SCHEMBL4738555 | 0.74 | ADAM17 (0.39) | ADAM17 | |
| SCHEMBL5066412 | 0.73 | MAOB (0.35) | ADAM17MAOBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076046-A1 | NOVEL 2-AMINO-5, 5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | disclosed |