Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737950 | 0.93 | POLB (0.42) | DRD2DRD4HTR1ASMOALDH1A1 | |
| SCHEMBL4738777 | 0.89 | MAPT (0.44) | DRD4DRD3HTR1AHTR2AALDH1A1 | |
| SCHEMBL4737202 | 0.82 | SLC6A9 (0.43) | HTR2ASMOALDH1A1KDM4EPOLB | |
| SCHEMBL4739773 | 0.81 | SLC6A9 (0.45) | HTR2ASMOALDH1A1KDM4EPOLB | |
| SCHEMBL4735222 | 0.79 | SMO (0.40) | HTR2ASMOALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4784363 | 0.78 | SMO (0.43) | SMOALDH1A1 | |
| SCHEMBL4739086 | 0.78 | TSHR (0.52) | DRD2DRD4DRD3HTR1AHTR2A | |
| SCHEMBL4740808 | 0.77 | SLC6A9 (0.44) | SMOALDH1A1 | |
| SCHEMBL3823818 | 0.74 | AGER (0.48) | DRD2HTR1AHTR2ASMOALDH1A1 | |
| SCHEMBL25911207 | 0.71 | OPRM1 (0.47) | ALDH1A1MAPTKDM4EPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |