Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739773 | 0.99 | SLC6A9 (0.45) | SLC6A9SLC6A5ALDH1A1KDM4ESMO | |
| SCHEMBL4735222 | 0.91 | SMO (0.40) | ALDH1A1KDM4ESMOHTR2ACYP1A2 | |
| SCHEMBL3823818 | 0.90 | AGER (0.48) | SLC6A9SLC6A5ALDH1A1KDM4ESMO | |
| SCHEMBL4737950 | 0.90 | POLB (0.42) | ALDH1A1KDM4ESMOCYP1A2CYP3A4 | |
| SCHEMBL4784363 | 0.88 | SMO (0.43) | SLC6A9SLC6A5ALDH1A1SMONPSR1 | |
| SCHEMBL4740808 | 0.87 | SLC6A9 (0.44) | SLC6A9SLC6A5ALDH1A1SMONPSR1 | |
| SCHEMBL8179598 | 0.85 | HTR2A (0.57) | SLC6A9SLC6A5ALDH1A1HTR2ANPSR1 | |
| SCHEMBL3827281 | 0.85 | AGER (0.54) | SLC6A9SLC6A5HTR2AL3MBTL1KMT2A | |
| SCHEMBL3827832 | 0.83 | AGER (0.53) | SLC6A9SLC6A5HTR2AL3MBTL1KMT2A | |
| SCHEMBL4735133 | 0.82 | DRD2 (0.45) | ALDH1A1KDM4ESMOHTR2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |