Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784363 | 0.99 | SMO (0.43) | SLC6A9SLC6A5SMOAGERMTNR1A | |
| SCHEMBL4739773 | 0.88 | SLC6A9 (0.45) | SLC6A9SLC6A5SMOAGERMTNR1A | |
| SCHEMBL4737202 | 0.87 | SLC6A9 (0.43) | SLC6A9SLC6A5SMOAGERMTNR1A | |
| SCHEMBL3063852 | 0.83 | SLC6A9 (0.41) | SLC6A9SLC6A5L3MBTL1ALDH1A1RORC | |
| SCHEMBL3058310 | 0.81 | HRH3 (0.40) | SLC6A9SLC6A5ALDH1A1RORC | |
| SCHEMBL4735235 | 0.80 | GAA (0.47) | SMO | |
| SCHEMBL4737580 | 0.80 | AGER (0.51) | AGERMTNR1ANPSR1L3MBTL1CHRM2 | |
| SCHEMBL4735222 | 0.79 | SMO (0.40) | SMOALDH1A1KLKB1KLK1 | |
| SCHEMBL4738735 | 0.78 | AGER (0.49) | AGERMTNR1ANPSR1L3MBTL1CHRM2 | |
| SCHEMBL4735133 | 0.77 | DRD2 (0.45) | SMOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |