Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.46 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784207 | 0.83 | L3MBTL1 (0.44) | RAB9ANPC1L3MBTL1RIPK1CNR2 | |
| SCHEMBL4731511 | 0.78 | L3MBTL1 (0.42) | RAB9ANPC1L3MBTL1RIPK1CNR2 | |
| SCHEMBL4783898 | 0.77 | CNR2 (0.46) | RAB9ANPC1L3MBTL1CNR2LMNA | |
| SCHEMBL4732956 | 0.74 | LMNA (0.40) | RAB9ANPC1L3MBTL1RIPK1CNR2 | |
| SCHEMBL4731606 | 0.73 | CNR2 (0.70) | CNR2CNR1 | |
| SCHEMBL4730468 | 0.73 | CNR2 (0.43) | RAB9ANPC1L3MBTL1CNR2LMNA | |
| SCHEMBL4733945 | 0.73 | CNR2 (0.43) | RAB9ANPC1L3MBTL1RIPK1CNR2 | |
| SCHEMBL14206941 | 0.72 | CNR2 (0.42) | RAB9ANPC1L3MBTL1RIPK1CNR2 | |
| SCHEMBL14207102 | 0.72 | CNR2 (0.44) | RAB9ANPC1L3MBTL1RIPK1CNR2 | |
| SCHEMBL4733265 | 0.70 | CNR2 (0.46) | RAB9ANPC1L3MBTL1RIPK1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |