Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735161 | 0.83 | RAB9A (0.46) | L3MBTL1NPC1RAB9ARIPK1HTT | |
| SCHEMBL14207113 | 0.81 | CNR2 (0.41) | NPC1RAB9ASMN1; SMN2CNR2MAPT | |
| SCHEMBL4732528 | 0.76 | CNR2 (0.39) | L3MBTL1NPC1RAB9ACNR2MEN1 | |
| SCHEMBL4732956 | 0.74 | LMNA (0.40) | L3MBTL1NPC1RAB9ARIPK1ADORA1 | |
| SCHEMBL4783898 | 0.74 | CNR2 (0.46) | L3MBTL1NPC1RAB9ABRD4HTT | |
| SCHEMBL4730468 | 0.72 | CNR2 (0.43) | L3MBTL1NPC1RAB9ACNR2KDM4E | |
| SCHEMBL4784212 | 0.72 | SMN1; SMN2 (0.44) | L3MBTL1PTGER1SMN1; SMN2BRD4STAT3 | |
| SCHEMBL4731511 | 0.71 | L3MBTL1 (0.42) | L3MBTL1NPC1RAB9ARIPK1HTT | |
| SCHEMBL4781292 | 0.69 | HTT (0.54) | L3MBTL1SMN1; SMN2BRD4STAT3HTT | |
| SCHEMBL4733265 | 0.68 | CNR2 (0.46) | L3MBTL1NPC1RAB9ARIPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |