Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738359 | 0.91 | LMNA (0.41) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL4737963 | 0.90 | MEN1 (0.39) | KDM4EALDH1A1TSHRCETPSLC6A7 | |
| SCHEMBL4739654 | 0.89 | LMNA (0.38) | ALDH1A1TSHRL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL4739647 | 0.88 | AR (0.43) | KDM4EALDH1A1L3MBTL1HTTGAA | |
| SCHEMBL4738694 | 0.86 | ACHE (0.43) | KDM4EALDH1A1TSHRDRD2DRD4 | |
| SCHEMBL4737079 | 0.86 | MEN1 (0.38) | KDM4EALDH1A1TSHRHTTCXCR2 | |
| SCHEMBL4734180 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1TSHRMAPK14 | |
| SCHEMBL4735114 | 0.85 | SMN1; SMN2 (0.41) | KDM4EALDH1A1TSHRL3MBTL1HTT | |
| SCHEMBL4737001 | 0.85 | CYP3A4 (0.37) | ALDH1A1TSHRHTTSMN1; SMN2HTR1A | |
| SCHEMBL3061194 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1TSHRL3MBTL1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |