Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737963 | 0.89 | MEN1 (0.39) | MEN1KMT2ACXCR2MAPTRECQL | |
| SCHEMBL4738694 | 0.86 | ACHE (0.43) | MAPTMAPK14ALDH1A1KDM4ETSHR | |
| SCHEMBL4735240 | 0.86 | KDM4E (0.44) | MEN1KMT2ACXCR2MAPK14ALDH1A1 | |
| SCHEMBL4739654 | 0.86 | LMNA (0.38) | MEN1KMT2ACXCR2MAPTRECQL | |
| SCHEMBL4738359 | 0.85 | LMNA (0.41) | MEN1KMT2ACXCR2MAPTALDH1A1 | |
| SCHEMBL4734180 | 0.85 | KDM4E (0.41) | MAPK14ALDH1A1KDM4ETSHR | |
| SCHEMBL4739647 | 0.84 | AR (0.43) | MAPTRECQLALDH1A1KDM4EGAA | |
| SCHEMBL4737001 | 0.83 | CYP3A4 (0.37) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL3061742 | 0.82 | MEN1 (0.40) | MEN1KMT2ACACNA2D1CACNA1BCACNB1 | |
| SCHEMBL4735114 | 0.81 | SMN1; SMN2 (0.41) | MEN1KMT2AMAPTMAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |